משרות והצעות עבודה

A hands-on Supply Chain & Logistics Manager for a growing medical device startup, with a product already in the commercialization stage and initial global sales, to take ownership of the company’s day-to-day supply chain and logistics operations. This role is well suited for an early-career supply chain professional (3–5 years of experience) who is looking to take on broad responsibility in a startup environment and gain end-to-end exposure to global supply chain operations. The company manufactures through a contract manufacturer in Northern Israel and works with international suppliers, including vendors in China. Key Responsibilities • Manage day-to-day supply chain operations, including procurement, vendor coordination, logistics, and inventory tracking. • Serve as the primary operational interface with the contract manufacturer, ensuring smooth production planning and material availability. • Coordinate with international suppliers and vendors, including order management and supplier communication. • Manage global shipments and logistics, including import/export processes and coordination with freight forwarders. • Track inventory levels and support basic demand and production planning. • Support cost control initiatives and operational efficiency improvements. • Maintain and improve ERP-based operational workflows related to purchasing, inventory, and logistics. • Ensure proper documentation and operational processes, including support for cloud-based document management. • Work closely with R&D, QA/RA, and Finance to ensure smooth operational execution. Location: Krayot area

A business-oriented and hands-on CEO for an innovative medical device startup in the surgical field. Following successful pre-clinical stages, the company is now entering critical clinical trials and global regulatory phases, seeking a leader to drive fundraising and strategic growth. Key Responsibilities: Fundraising & Investor Relations: Lead equity financing rounds and secure investments from VCs and strategic partners. Strategic Leadership: Define and execute the company’s business strategy and clinical validation pathways. Clinical & Regulatory Oversight: Oversee clinical trials in Israel and Europe; manage FDA and CE regulatory tracks. Team Management: Lead a multidisciplinary team and subcontractors through manufacturing and V&V completion. Business Development: Build relationships with KOLs and industry partners. Location: North District, Israel

• Content Creation: Develop high-quality, engaging, and informative content for various digital platforms for a B2B (physicians, distributors) audience in the medical field including blogs, social media, websites, videos, and email newsletters. Includes creating visuals to accompany posts and e-mail. • Social Media Management: Plan, create, and schedule social media posts. Monitor and respond to audience engagement and trends. • SEO Optimization: Implement SEO best practices to increase organic traffic and search engine rankings. • Analytics and Reporting: Track and analyze the performance of digital content and campaigns. Provide regular reports and insights to optimize strategies. • Brand Consistency: Ensure all content aligns with Companie's brand voice, guidelines, and goals. • Collaboration: Work closely with cross-functional teams including product, sales, and clinical departments to gather information and create cohesive content strategies. • Event Promotion: Create promotional content for events, webinars, and product launches to drive attendance and engagement. • Build Partner Marketing Strategies: Provide our global partners with ideas and methods to utilize our content or develop content for their own local campaigns of Companie’s products and initiatives. • Internal Communications: Assist as needed to promote brand awareness and messaging, support company events. • Marketing Operations: Perform administrative tasks related to managing marketing vendors and conference logistics. Location: Sharon district, Israel (Hybrid)

A leading medical device company is seeking an experienced Sales Territory Manager to expand market presence, increase revenue, and build strong, long-term customer partnerships throughout Israel. RESPONSIBILITIES: •Consistently achieve or exceed sales targets •Identify customer needs and tailor solutions accordingly •Build and maintain trust-based relationships with physicians and hospital staff •Provide product demonstrations and clinical support •Negotiate with hospital purchasing departments •Stay informed on competitor activities and market dynamics •Ability to travel abroad for conferences and later on for managing international distributors

This role is responsible for ensuring compliance, quality, and operational excellence throughout the development and manufacturing of Class III medical devices. Responsibilities • Ensure compliance with FDA regulations, ISO 13485/14971, EU MDR, and applicable standards. • Lead and manage CAPA, complaints handling, standards gap analysis, internal audits, and management reviews. • Oversee and support MRB activities, change control, process controls, validations (PV, EQ), pFMEA, risk management, and statistical process monitoring. • Prepare for and support external and internal audits (FDA, ISO, Notified Bodies). • Collaborate with cross-functional teams and train staff on QA best practices. Location: Sharon district, Israel (Hybrid)

This role is responsible for ensuring compliance, quality, and operational excellence throughout the development and manufacturing of Class III medical devices. Responsibilities • Lead, mentor, and manage the QA team, including task prioritization and performance development • Maintain and continuously improve the Quality Management System in compliance with ISO 13485, EU MDR, and FDA QSR (21 CFR 820) • Support Operations activities, including manufacturing, validation, MRB, CAPA, and supplier quality • Oversee CAPA, nonconformances, deviations, complaints, risk management, document control, and training processes • Prepare, implement, and maintain quality plans and annual quality activities • Actively participate in and support internal, supplier, and regulatory audits, including preparation, execution, and follow-up • Support regulatory submissions and interactions as required • Ensure quality oversight of QMS modules • Collaborate cross-functionally with R&D, Regulatory Affairs, Operations, and Clinical teams • Promote a strong culture of quality, compliance, and continuous improvement

Looking for a dynamic and experienced Director of Sales Europe, to lead sales efforts across Europe, consistently delivering Annual Recurring Revenue (ARR) targets. You will collaborate closely with Customer Success, Marketing, and Product teams for a leading Israeli software company. Role Overview Your primary focus will be overseeing sales activities and negotiations, fostering new business opportunities, and scaling subscription-based growth through complex B2B software-hardware integration projects. Tasks that you might work on include, but are not limited to: Enterprise Growth: Be the driving force behind efforts to generate new Enterprise business opportunities, overseeing the entire B2B sales cycle. Customer Base Expansion: Strategically expand the customer base through effective relationship-building using a consultative sales approach. Client Engagement: Identify and comprehend the strengths and needs of the existing client pipeline, ensuring tailored solutions that meet their requirements. On-Site Visits: Plan and execute successful on-site visits with prospective customers, fostering trust and collaboration. Product Demos: Conduct compelling online product demonstrations that showcase the value of the company's software integration platform. Contract Negotiations: Lead contract negotiations to secure mutually beneficial agreements.

A Customer Success Manager in Japan will report directly to our VP Business Development or to the CEO, and will look over our business activity in the country. They will be responsible for existing costumers, retention, conducting meetings with existing and new local customers. They will be the liaison between our Marketing, Sales, and R&D, overlooking projects throughout, and maintaining a close and ongoing relationship with local customers. Location: Tokyo\Yokohama

• Conduct Incoming Inspection, QC, and in-process control activities per procedure and product requirements. • Support product/Batch release. • Write, review, and approve procedures and work instructions. • Provide support in the maintenance and improvement of the QMS. • Participate in product quality investigations in support of CAPA and Nonconforming material processes. • Support continuous improvement activities to reduce product failure rates. • Reviewing data and conducting statistical analysis • Collaborate with other departments and CMs functions to ensure high-level quality standards. • Performing Internal and External Audits • Represent Quality in a core team of different projects. • Supporting activities required to ensure Subcontractors and Supplier’s compliance with Company’s requirements. • Evaluating and supporting Suppliers and subcontractors’ quality performance • Take an active role in reviewing and approving design and manufacturing changes. • Participate in ongoing processes to improve products and services. • Verify the compliance of the company’s quality and control system requirements with regulation standards and company’s policies.

In this role, you’ll work closely with cross-functional teams, execute day-to-day quality activities on the manufacturing floor and help drive continuous improvement in a hands-on, fast-paced environment. Responsibilities: • Manage ECOs: conduct risk assessments, update relevant DMR documents and carry out necessary IQ, OQ, PQ activities if required, finalization of implementation tasks. • Manage DCOs in the PLM system: Write and update QA procedures to ensure compliance with quality standards and regulatory requirements. • Manage NCR and CAPA processes: Lead, write and supervise the NCR and CAPA processes, ensuring timely and effective resolutions. • Manage QA production activities: Provide quality support to production operations, addressing deviations and non-conformities to maintain high product quality. • Ensuring Timely Resolution of Quality Issues: Promptly address all identified or assigned quality issues to prevent delays and maintain efficient operations. • Participate in audits: Take part in internal and external audits, such as FDA inspections and notified body audits based on ISO13485, EUMDR, and MDSAP requirements. • Supplier Quality Management: Manage supplier qualification and performance monitoring, including SCAR management, and support supplier audits.

General position. Here you can submit your CV that will enter our database. We will reach out to you as soon as a position opens. * שליחת קורות חיים למשרה זו מהווה אישור לשמירתם במאגר המידע של סטפ אפ קריירה, לצורך טיפול במשרה זו ו/או משרות נוספות. בכל שלב תוכל.י לבקש עיון או מחיקה

• Overall responsibility for the Quality Management System, including ownership and leadership of QMS processes such as CAPA, Complaints, Document Control, Training, Internal and External Audits, and Supplier Quality • Lead, maintain, and continuously improve the QMS to ensure compliance with applicable regulatory and quality standards • Manage and develop QMS processes and procedures, ensuring effective implementation across the organization • Monitor and assess QMS performance, identify gaps and improvement opportunities, and drive corrective and preventive actions • Prepare and present QMS-related data and metrics for Management Review and quality forums • Lead internal audits and support external and regulatory audits • Provide professional guidance, training, and support to stakeholders on QMS-related topics

Role summary Reporting directly to the CEO, the Vice President, CMC & Technical Operations will own end to end CMC and technical operations for preclinical and clinical stage RNA targeting oligonucleotide programs, including complex lipid / liposomal formulations. The role has two main functions: (1) hands-on management of the company’s chemical R&D and R&D scale manufacturing facility and (2) management of external development contracts and supply for both preclinical GLP-like and clinical GMP manufacturing at CDMOs. The person will be responsible from late stage process development and validation through clinical supply and preparation for commercialization, including leadership of CMC contributions to global regulatory filings. Key responsibilities • Set the overall CMC and technical operations vision and roadmap for oligonucleotide drug substance and lipid / liposomal injectable drug product from Phase 1/2 through Phase 3 and commercialization, aligned with Companie's corporate strategy. • Manage the team and activities of the facility in Jerusalem, to ensure alignment with company strategy. Support the team in process development, yield improvement, etc. • Lead selection, contracting input, and day to day technical, operational, and quality oversight of global CDMOs/CMOs for DS and DP, including oligo synthesis, purification, conjugation, liposomal formulation, sterile fill/finish, packaging, and testing. • Design and oversee process validation strategies (including PPQ) and implement robust control strategies and continued process verification for both DS and DP suitable for global registrations. • Direct analytical development, method qualification/validation, and stability programs for DS, DP, and critical raw materials (e.g., lipids, modifications) to support specifications, shelf life, and comparability. • Serve as CMC lead for all regulatory interactions: drive authoring, review, and maintenance of CMC sections of IMPD/IND/CTA and later stage dossiers (e.g., NDA/MAA), and coordinate timely, science based responses to health authority questions. • Ensure phase appropriate CMC documentation, including master batch records, specifications, validation protocols and reports, deviations, investigations, and change controls generated with CDMOs. • Partner closely with Research, Clinical, Clinical Operations, and Clinical Supply to forecast needs and ensure uninterrupted GMP supply for global trials, including labeling, distribution, and returns strategy. • Build and maintain a resilient, cost effective global supply chain for oligonucleotide and liposomal products, including risk identification, mitigation plans, and contingency strategies for single source materials and sites. • Contribute to portfolio and program decision making with the CEO and executive team, providing CMC/Tech Ops input on timelines, risks, budgets, and scenario planning. • Recruit, lead, and develop a small, high caliber internal CMC/Technical Operations team; establish clear objectives, governance, and ways of working with internal and external partners. • Support due diligence and technical assessments of new pipeline assets, delivery technologies, and manufacturing partners relevant to RNA targeting oligonucleotide therapeutics.

Experienced and visionary CEO to lead an early-stage pharmaceutical company developing an innovative drug product. This is a unique opportunity to shape the strategy, secure the funding, and lead the development of a high-potential therapeutic candidate. Key Responsibilities: • Define and execute the company’s strategic and operational plans, in alignment with the Board’s vision. • Lead the company’s fundraising efforts, including interactions with VCs, angel investors, and strategic partners. • Establish strategic collaborations and co-development agreements with pharma and biotech partners. • Oversee and manage all R&D activities, including budget, timeline, and milestone tracking. • Lead the non-clinical development of the company’s lead asset. • Develop and adjust the clinical and regulatory roadmap in collaboration with key experts and partners. This is a full-time, on-site position (not hybrid), based in the Northern District of Israel.

General position. Here you can submit your CV that will enter our database. We will reach out to you as soon as a position opens. • שליחת קורות חיים למשרה זו מהווה אישור לשמירתם במאגר המידע של סטפ אפ קריירה, לצורך טיפול במשרה זו ו/או משרות נוספות. בכל שלב תוכל.י לבקש עיון או מחיקה

General position. Here you can submit your CV that will enter our database. We will reach out to you as soon as a position opens. * שליחת קורות חיים למשרה זו מהווה אישור לשמירתם במאגר המידע של סטפ אפ קריירה, לצורך טיפול במשרה זו ו/או משרות נוספות. בכל שלב תוכל.י לבקש עיון או מחיקה